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flow-count radioactivity detector  (LabLogic Systems Ltd)

 
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    Structured Review

    LabLogic Systems Ltd flow-count radioactivity detector
    Flow Count Radioactivity Detector, supplied by LabLogic Systems Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/flow-count radioactivity detector/product/LabLogic Systems Ltd
    Average 90 stars, based on 1 article reviews
    flow-count radioactivity detector - by Bioz Stars, 2026-06
    90/100 stars

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    PET studies of brain in monkey A with [18F]PS13 (carrier PS13:6.6 nmol/kg at baseline). Panel A: regional VT images from baseline scan (top row) and blocked scans (with PS13, 0.3 mg/kg, i.v.) (middle row), and corresponding MRI images (bottom row). Left column: coronal images; middle column: sagittal images; right column: horizontal images. Highest <t>radioactivity</t> uptake occurred in the prefrontal and parietal cortices. Panel B: whole brain time-activity curves at baseline and after preblock obtained with [18F]PS13. Corresponding curves obtained in a different monkey with [11C]PS13 from the study in ref 17 with a much lower PS13 carrier dose (0.19 nmol/kg at baseline) are shown for comparison.
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    Image Search Results


    PET studies of brain in monkey A with [18F]PS13 (carrier PS13:6.6 nmol/kg at baseline). Panel A: regional VT images from baseline scan (top row) and blocked scans (with PS13, 0.3 mg/kg, i.v.) (middle row), and corresponding MRI images (bottom row). Left column: coronal images; middle column: sagittal images; right column: horizontal images. Highest radioactivity uptake occurred in the prefrontal and parietal cortices. Panel B: whole brain time-activity curves at baseline and after preblock obtained with [18F]PS13. Corresponding curves obtained in a different monkey with [11C]PS13 from the study in ref 17 with a much lower PS13 carrier dose (0.19 nmol/kg at baseline) are shown for comparison.

    Journal: ACS chemical neuroscience

    Article Title: Synthesis of [ 18 F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey

    doi: 10.1021/acschemneuro.0c00737

    Figure Lengend Snippet: PET studies of brain in monkey A with [18F]PS13 (carrier PS13:6.6 nmol/kg at baseline). Panel A: regional VT images from baseline scan (top row) and blocked scans (with PS13, 0.3 mg/kg, i.v.) (middle row), and corresponding MRI images (bottom row). Left column: coronal images; middle column: sagittal images; right column: horizontal images. Highest radioactivity uptake occurred in the prefrontal and parietal cortices. Panel B: whole brain time-activity curves at baseline and after preblock obtained with [18F]PS13. Corresponding curves obtained in a different monkey with [11C]PS13 from the study in ref 17 with a much lower PS13 carrier dose (0.19 nmol/kg at baseline) are shown for comparison.

    Article Snippet: The HPLC apparatus for [ 18 F]PS13 separation comprised a pump (P4.1S; Knauer; Berlin, Germany), a UV absorbance detector (UVD2.1S; Knauer), and a radioactivity detector (flow-count; Eckert & Ziegler; Berlin, Germany).

    Techniques: Radioactivity, Activity Assay, Comparison

    Plasma clearance and metabolism of [18F]PS13 in monkey A. Panel A: reversed phase HPLC analysis of radiometabolites in plasma at 180 min after intravenous radioligand injection at baseline. Panel B: time-course of the percentage of radioactivity in plasma represented by unchanged [18F]PS13 under baseline and preblocked conditions. Panel C: time-course for unchanged [18F]PS13 in plasma under baseline and preblocked conditions.

    Journal: ACS chemical neuroscience

    Article Title: Synthesis of [ 18 F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey

    doi: 10.1021/acschemneuro.0c00737

    Figure Lengend Snippet: Plasma clearance and metabolism of [18F]PS13 in monkey A. Panel A: reversed phase HPLC analysis of radiometabolites in plasma at 180 min after intravenous radioligand injection at baseline. Panel B: time-course of the percentage of radioactivity in plasma represented by unchanged [18F]PS13 under baseline and preblocked conditions. Panel C: time-course for unchanged [18F]PS13 in plasma under baseline and preblocked conditions.

    Article Snippet: The HPLC apparatus for [ 18 F]PS13 separation comprised a pump (P4.1S; Knauer; Berlin, Germany), a UV absorbance detector (UVD2.1S; Knauer), and a radioactivity detector (flow-count; Eckert & Ziegler; Berlin, Germany).

    Techniques: Clinical Proteomics, Injection, Radioactivity